A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

Abstract Background Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that Handlebar Front block HIV transmission from one individual to another.Therefore, virucidal agents that inactivate HIV virions may be used as a component in topical microbicides.Results

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